The effect of replacing animal-based proteins with plant-based proteins on metabolic syndrome treatment

The comparison of the effectiveness of replacing animal-based proteins with plant-based proteins on adropin levels, atherogenic index of plasma, and metabolic syndrome components in subjects with metabolic syndrome.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150909023957N10

Enrollment

Registered

2022-05-16

Start date

2022-05-22

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic syndrome. Metabolic syndrome

Interventions

Intervention 1: Intervention group: Plant-based protein diet (diet containing 30% animal protein and 70% plant protein). Intervention 2: Control group: Animal-based protein diet (diet containing 70% a

Eligibility

Sex/Gender

All

Age

20 Years to 55 Years

Inclusion criteria

Inclusion criteria: Desire to participate in the study Male and female teachers working in Isfahan Age 20 to 55 years and Iranian nationality Diagnosis of metabolic syndrome based on JIS criteria Body mass index between 25 to 35 kg/m2

Exclusion criteria

Exclusion criteria: Follow a special diet for the past 6 months Dietary supplements use History of kidney, liver, cardiovascular, thyroid and cancer diseases Use of hormonal drugs, birth control pills, glucocorticoids and drugs to lower blood sugar, blood pressure and lipids Pregnancy and lactation Alcohol, cigarettes and tobacco use

Design outcomes

Primary

Measure	Time frame
Adropin. Timepoint: Initiation and end of the study (after 10 weeks). Method of measurement: ELISA.;The atherogenic index of plasma (AIP). Timepoint: Initiation and end of the study (after 10 weeks). Method of measurement: Log (TG/HDL_C).;Component of metabolic syndrome including fasting blood sugar, lipid profile, waist circumference, and blood pressure. Timepoint: Initiation and end of the study (after 10 weeks). Method of measurement: Fasting blood sugar and lipid profile by enzymatic method and auto-analyzer, waist circumference using tape measure and blood pressure using Omron Upper arm Blood Pressure.	—

Measure

Time frame

Adropin. Timepoint: Initiation and end of the study (after 10 weeks). Method of measurement: ELISA.;The atherogenic index of plasma (AIP). Timepoint: Initiation and end of the study (after 10 weeks). Method of measurement: Log (TG/HDL_C).;Component of metabolic syndrome including fasting blood sugar, lipid profile, waist circumference, and blood pressure. Timepoint: Initiation and end of the study (after 10 weeks). Method of measurement: Fasting blood sugar and lipid profile by enzymatic method and auto-analyzer, waist circumference using tape measure and blood pressure using Omron Upper arm Blood Pressure.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSayyed Morteza Safavi

Esfahan University of Medical Sciences

safavimorteza@yahoo.com+98 31 3792 3168

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026