effectiveness of local Tranexamic Acid on Epistaxis Control in patients with antiplateletes therapy(ASA, plavix)

camparison of local Tranexamic Acid with anterior nasal packing in control of epistaxis in patients with antiplatelets therapy(ASA, Plavix) whom referring with anterior nasal bleeding.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201509088872N9

Enrollment

100

Registered

2015-09-25

Start date

2015-10-12

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epistaxis. ??????? ?? ????

Interventions

Intervention 1: Tranexamic Acid: Ampoule, 100mg/ml, Local, the wick is soaked in 5cc of solution. Intervention 2: Epinephrine 1/100000 and Lidocine 2%, Solution, Local, the wick is soaked in 5cc of so

Treatment - Drugs

Tranexamic Acid: Ampoule, 100mg/ml, Local, the wick is soaked in 5cc of solution

Epinephrine 1/100000 and Lidocine 2%, Solution, Local, the wick is soaked in 5cc of solution.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion Criteria: All patients with epistaxis and history of consumption of ASA and Plavix whom referring to the emergency department. Exclusion Criteria: Trauma patients; history of anticoagulants drug consumption; Inherited bleeding disorders; Hemophiliacs; Inherited platelet disorders; Shock; Lack of consent; patients with visible bleeding vessel; history of renal disease; INR> 1.5

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Bleeding control time. Timepoint: every 5 minutes from the start point until the bleeding stops. Method of measurement: measured by stopwatch, per minute.	—

Secondary

Measure	Time frame
Bleeding recurrence. Timepoint: first 24 hours and the first week. Method of measurement: measured by watch.;Patient's satisfaction. Timepoint: within discharge. Method of measurement: by VAS measurment system (10 points mark).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Morteza Saeedi

Tehran University of Medical Sciences

m_saeedi@tums.ac.ir+98 21 8490 2719

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026