Pain after abdominal hystrectomy. Postprocedural disorder of genitourinary system, unspecified
Conditions
Interventions
Intervention 1: No prescription 2 hours before the TAH in control group. Intervention 2: Melatonin Tablet(5 mg) prescription 2 hours before the TAH in intervention group. Intervention 3: Prega
Treatment - Drugs
No prescription 2 hours before the TAH in control group
Melatonin Tablet(5 mg) prescription 2 hours before the TAH in intervention group
Pregabalin Capsule(50 mg) prescription 2 hours before the TAH in intervention group
Sponsors
Vice Chancellor for Research-Guilan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
35 Years to 55 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria:Totalm Abdominal Hystrectomy; Age 35-55; ASA I,II Exclusion criteria: Patients in consider to Cardial; Pulmonary; hepatic; Renal; autoimmune; pscychologic; gastrointestinal diseases; Diabetis; sleep disorders; Epilepsia; Nystagmous; Leukemia; speech and hearing disorders; seasonal and drug allergies; chronic analgesia; hypnotics; pscychotropic; opioid; Beta blockers and MAOI consumption; adverse drug reactions; patients refuse to collaboration.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregabalin(50 mg) with a glass of water. Timepoint: Two hours before the surgery. Method of measurement: mg/kg.;Melatonin. Timepoint: Two hours before the surgery. Method of measurement: Mg/kg.;Fentanyl. Timepoint: Hours(1-6-12-24). Method of measurement: µg/kg. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intense of pain. Timepoint: During first hour after the. Method of measurement: surgery.;Serum Melatonin. Timepoint: During first hour after the surgery. Method of measurement: pg/mL.;Serum Beta Endorphin. Timepoint: During first hour after the surgery. Method of measurement: ng/L. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Katayoun Haryalchi
Guilan university of Medical Sciences
Outcome results
None listed