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Sertraline effectiveness in prevention of depression in MS patients.

Sertraline effectiveness in prevention of depression, fatigue reduction and QOL improvement in MS patients.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015090723927N1
Enrollment
60
Registered
2015-11-02
Start date
2015-09-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis. Multiple sclerosis

Interventions

Intervention 1: In study group we will add 50 mg sertraline produced by sobhan manufacture every day for six months,this group will consider at the beginning ,end of 1th month, 3th month and end 6th
Prevention
Placebo
In study group we will add 50 mg sertraline produced by sobhan manufacture every day for six months,this group will consider at the beginning ,end of 1th month, 3th month and end 6th month for depres
In control group we will add one placebo produced by pharmacy faculty of Tabriz university of medical science for six months every day . They will consider at the beginning , end of 1th month ,3th mon

Sponsors

Vice chancellor for research,Tabriz university of medical science.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
79 Years to 34 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Age 15-60;Primary education Exclusion; Other Organic illnesses:Other mental disorder;Smoking and substance induce or alcohol abuser.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Depresion. Timepoint: Atfirst of study, 1 mth later, 3mth later, 6 mth later. Method of measurement: Hamilton Questionnaire.;Decreament OF Fatigue. Timepoint: Atfirst of study, 1 mth later, 3mth later, 6 mth later. Method of measurement: SF_36 Questionnaire.;Quality of life. Timepoint: Atfirst of study, 1 mth later, 3mth later, 6 mth later. Method of measurement: FSS Questionnaire OF QOL.

Secondary

MeasureTime frame
Probably switch to mania. Timepoint: During fallow up times. Method of measurement: Based on DSM criteria.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Askarpour

Tabriz university of medical science

info@medfac.tbzmed.ac.ir+98 41 3336 4667

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026