Anesthesia and delivery. Complications of anaesthesia during labour and delivery
Conditions
Interventions
Intervention 1: Intervention Group(1): 50 milliliter normal saline is injected intravenously during 15 minutes at the beginning of surgery .then 10 milliliter of 0.5%bupivacaine which is diluted with
Treatment - Drugs
Placebo
Intervention Group(1): 50 milliliter normal saline is injected intravenously during 15 minutes at the beginning of surgery .then 10 milliliter of 0.5%bupivacaine which is diluted with 10 milliliter o
Intervention group (2): At the beginning of surgery 50 milliliter normal saline intravenously injected. Then 0.1 milliliter of adrenaline 1:1000 + 10 milliliter of 0.5% bupivacaine is diluted with nor
Intervention group (3): 50 milligrams per kilogram of magnesium sulfate 50% by volume of 50 milliliter normal saline can be injected intravenously over 15 minutes And 10 milliliter 0.5% bupivacaine wi
Control group: 50 milliliter normal saline injected intravenously over 15 minutes, and 20 milliliter normal saline injected in subcutaneous fat after repairing fascia
Sponsors
Vice chancellor for research, Babol University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion criteria: Term Pregnancy; single pregnancy; ASA class I or II; Height 180 to 170 cm,; End pregnancy weight from 100 to 70 kg and undergoing elective cesarean section. Exclusion criteria: having hypersensitivity to amide local anesthetics (eg, bupivacaine and lidocaine), magnesium sulfate and epinephrine; history of opioid drugs; coagulopathy; seizure; cardiovascular disease; mental disorders; asthma and chronic obstructive pulmonary disease; high ICP; kidney disease; liver disease; atrioventricular block; history of calcium channel blockers; A tonic uterus after surgery or prolong surgical time more than 1.5 hours
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of pain. Timepoint: 2, 6, 12, 18 and 24 hours after after starting the intervention. Method of measurement: visual Analogous Scale of pain. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: 2, 6, 12, 18 and 24 hours after starting intervention. Method of measurement: Observation and record.;Heart rate. Timepoint: 2, 6, 12, 18 and 24 hours after starting intervention. Method of measurement: Observation and record. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRabeeh Rouhani
Babol university of medical science
Outcome results
None listed