Breast Cancer. Malignant neoplasm of breast
Conditions
Interventions
Intervention 1: Placebo, one time per week for 2 months. Intervention 2: Vitamin D, 50,000 IU, one time per week for 2 months.
Placebo
Treatment - Drugs
Placebo, one time per week for 2 months
Vitamin D, 50,000 IU, one time per week for 2 months
Sponsors
Vice Chancellor for Research of Ahvaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: all women who were diagnosed with stage ? breast cancer; age>20 years; 23< BMI<30; not consuming any kinds of vitamin D supplements during last 3 month; not getting any medication that affect serum vitamin D status. Exclusion criteria: the presence of any underlying disease (liver, kidney and HIV); a history of chemotherapy or radiotherapy for any reason except for current cancer; treatment with Corticosteroids; pregnancy and lactation; chronic diarrhea and malabsorption; non-iranian races (foreigners).
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor Necrosis Factor alpha. Timepoint: At the beginning and the end of the study. Method of measurement: ELISA.;Transforming Growth Factor beta. Timepoint: At the beginning and the end of the study. Method of measurement: ELISA.;Total Antioxidant Capacity. Timepoint: At the beginning and the end of the study. Method of measurement: ELISA.;25 (OH) D. Timepoint: At the beginning and the end of the study. Method of measurement: ELISA.;Vitamin D receptor polymorphisms (FOK1? Bsml1? Taq? Apa1). Timepoint: At the beginning of the study. Method of measurement: PCR. | — |
Secondary
| Measure | Time frame |
|---|---|
| Antropometric Measurments (height, weight and waist circumferences). Timepoint: at the baseline and after 8 weeks of intervention. Method of measurement: Height, hip and waist circumferences in cm and weight in kg by standard method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHoura Mohseni
Ahvaz Jundishapur University of Medical Sciences
Outcome results
None listed