Condition 1: AML. Condition 2: ALL. Acute myeloblastic leukaemia [AML] Acute lymphoblastic leukaemia [ALL]
Conditions
Interventions
Intervention 1: In the control group, combination of midazolam 0/03 mg / kg and fentanyl 1 µg / kg and ketamine 1 mg / kg and propofol 1 mg / kg are injecting intravenously. Intervention 2: In the stu
Treatment - Drugs
In the control group, combination of midazolam 0/03 mg / kg and fentanyl 1 µg / kg and ketamine 1 mg / kg and propofol 1 mg / kg are injecting intravenously.
In the study group, combination of midazolam 0/03 mg / kg and fentanyl 1 µg / kg and ketamine 1 mg / kg and propofol 1 mg / kg are injecting intravenously and the patients are ventilated with entonox,
Sponsors
Vice Chancellor for Research and Technology,Shahid Beheshti University Of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 16 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:patients undergoing bone marrow biopsy (the first turn) exclusion criteria:History of asthma;Catching common cold;detection of any complications during the procedure ( apnea;%90 = SPo2;Bradycardia > %30 of baseline);Doing any previous procedure with sedation;Parent discontent;Not fasting;History of hypersensitivity to any of the drugs
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation scale. Timepoint: 1 minute. Method of measurement: Ramsay sedation scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery time. Timepoint: After the procedure. Method of measurement: minute.;SpO2. Timepoint: Before administration of drugs - immediately before the procedure - at the beginning of the procedure - at the end of the procedure. Method of measurement: Pulse Oximeter.;Heart rate. Timepoint: Before administration of drugs - immediately before the procedure - at the beginning of the procedure - at the end of the procedure. Method of measurement: Pulse Oximeter.;Physician satisfaction. Timepoint: During the procedure. Method of measurement: VAS (10-0).;Nurse satisfaction. Timepoint: During the procedure. Method of measurement: VAS (10-0). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehrdad Taheri
Shahid Beheshti University of Medical Sciences
Outcome results
None listed