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comparison of headache accurance and severity after use of phenylephtine and ephedrine for treatment of hypotention during cesarian delivery under spinal anesthesia

Comparison of headache prevalence and intensity following administration of ephedrine and phenylephrine in cesarean section under spinal anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201509042946N7
Enrollment
105
Registered
2016-12-07
Start date
2016-08-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

headache. Drug-induced headache, not elsewhere classified

Interventions

Intervention 1: Ephedrine ampule 10 mcgr, Intravenous, repeated until hemodynamic stability. Intervention 2: Phenylephrine ampule 50 mcgr, Intravenous, repeated until hemodynamic stability in the fir
Prevention
Ephedrine ampule 10 mcgr, Intravenous, repeated until hemodynamic stability
Phenylephrine ampule 50 mcgr, Intravenous, repeated until hemodynamic stability in the first case group

Sponsors

Vice chancellor for reasearch ,Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Pregnant women aged 18 to 40 years; ASA class I_II; systolic blood pressure 120-140 mmhg; body mass index 18.5_25 and normal single fetus pregnancy. Exclusion criteria: History of migraine; psychiatric disorders; any medication except pregnancy supplements; presence of headache in admission time to operation room; eclampsia; preeclampsia; hypertention; diabetes mellitus and cardiovascular disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Headache incidence and intencity. Timepoint: during cesarean, 1, 6, 24 hours later. Method of measurement: by visual analogue scale.

Secondary

MeasureTime frame
Vital sign changes. Timepoint: every 2 minute until 10minute then every 5 minute. Method of measurement: by datascope monitor.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mitra Yari

Kermanshah University of Medical Sciences

myari@kums.ac.ir+98 83 3433 4157

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026