acne vulgaris. acne vulgaris
Conditions
Interventions
Intervention 1: Topical tea tree oil nanoemulsion loaded 0.1% adapalene gell, one times daily on the clean skin for 3 months. Intervention 2: Topical adapalene gell 0.1%, one times daily on the clean
Treatment - Drugs
Topical tea tree oil nanoemulsion loaded 0.1% adapalene gell, one times daily on the clean skin for 3 months
Topical adapalene gell 0.1%, one times daily on the clean skin for 3 months
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Presence of mild to moderate Acne Vulgaris (up to 10 comedons, papular and/or pustular lesions). Exclusion criteria: pregnant and lactating women, children younger than 15 years old, severe cases of acne (existence of nodules and cysts), receiving anti acne during two weeks prior to study, taking acne creating drugs such as oral or local steroids, spirnolactone, finasteride. Patient with diabetes mellitus, endocrine disorder.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory and noninflammatory lesions. Timepoint: Baseline and after 4,8, and 12 weeks. Method of measurement: counting lesions using manual lens. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effect. Timepoint: Baseline and after 4, 8, and 12 weeks. Method of measurement: case report form. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRoqiye Najafi-Taher
Tehran University of Medical Sciences
Outcome results
None listed