Obesity And Overweight. Obesity due to excess calories
Conditions
Interventions
Intervention 1: Intervention groups: receive 50000 IU vit D once in first week as a blues and 2000 IU vit D per day from second week along with low calorie diet that which reduce the weight 0.5 to 1
Prevention
Placebo
Intervention groups: receive 50000 IU vit D once in first week as a blues and 2000 IU vit D per day from second week along with low calorie diet that which reduce the weight 0.5 to 1 kg every week f
control group: receive placebo of vitamin D (edible paraffin) with low calorie diet that which reduce the weight 0.5 to 1 kg every week for 8 weeks.
Sponsors
Vice chancellor for research, Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age of 20-50; BMI= 25-40; don’t taking the glucose and lipid- lowering drugs; interesting in participation in research; without any metabolic disease; CHD; diabetes; without autoimmune disease; cancer; without infection disease in research; no smoking; no alcoholism; without immune system suppressor drugs 6 mounts before research; no menstrual bleeding; without any diet 3 mounts before research; no consumption vit D supplementation and multivitamin mineral during research; without use of medication affecting Vitamin D metabolism; without use of tanning bed during the study and 3 months before study initiation; without renal and hepatic diseases; women without polycystic ovary syndrome exclusion criteria: metabolic; CHD; autoimmune disease and cancer; infection disease in research; smoking; alcoholism; use of immune system suppressor drugs 6 mounts before research; menstrual bleeding; diet 3 mounts before research; consumption vit D supplementation and multivitamin mineral during research; use of medication affecting Vitamin D metabolism; use of tanning bed during the study and 3 months before study initiation; Having renal and hepatic diseases; women with polycystic ovary syndrome; no interesting for participation
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Waist circumference. Timepoint: Before and after intervention. Method of measurement: meter.;Omentin, Spexin, sICAM-1. Timepoint: Before and after intervention. Method of measurement: ELIZA.;Fat percent. Timepoint: Before and after intervention. Method of measurement: BIA method.;BMI. Timepoint: Before and after intervention. Method of measurement: Formula.;Vitamin D. Timepoint: Before and after intervention. Method of measurement: ELIZA.;FBS, HDL-C. Timepoint: Before and after intervention. Method of measurement: Enzymatic Method.;Triglyceride, Total cholesterol. Timepoint: Before and after intervention. Method of measurement: Photometric.;LDL-C. Timepoint: Before and after intervention. Method of measurement: Enzymatic Method.;Hs-CRP. Timepoint: Before and after intervention. Method of measurement: Enzymatic Method.;Diastolic blood pressure. Timepoint: Before and after intervention. Method of measurement: manometer.;Exposure of sunlight. Timepoint: Before and after intervention. Method of measurement: questionnaire.;Systolic blood pressure. Timepoint: Before and after intervention. Method of measurement: manometer.;Nutritional status. Timepoint: Before and after intervention. Method of measurement: Measurement of energy and nutrients intake using 24-hour dietary recall method and anthropometric measurement using scale and stadiometer.;Phisical Activity. Timepoint: Before and after intervention. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mitra Zarrati
Iran University of Medical Sciences, School of Public Health
Outcome results
None listed