Acute Renal Colic. Urinary calculus, unspecified
Conditions
Interventions
Intervention 1: Intervention group: patients will receive 30 mg intravenous ketorolac tromethamine (brand name : ketorolac ,Caspian Tamin Pharmaceutical Company) within 15 seconds. Intervention 2: Con
Treatment - Drugs
Intervention group: patients will receive 30 mg intravenous ketorolac tromethamine (brand name : ketorolac ,Caspian Tamin Pharmaceutical Company) within 15 seconds.
Control group: patients will receive 1 gram intravenous paracetamol (brand name : Apotel) infused in 100 ml normal saline within 15 minutes.
Sponsors
Vice- Chancellor for Research, Semnan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Patients will eligible for inclusion with a history of unilateral abdominal or flank pain that the treating emergency physicians suspect to be renal colic, with ultrasonography or CT Scan or intravenous pyelography (IVP) findings consistent with the diagnosis of renal colic or passage of the calculus. Only patients displaying at least a visual analog scale (VAS) =30/100 will include. Patients can not be include if they have a history of peptic ulcer disease, asthma, bleeding disorder (including the use of oral anticoagulant), impaired renal or hepatic function, suspected hypersensivity to aspirin or NSAID or paracetamol, and if they are pregnant and breast-feeding women. Patients can not be include if they have received painkillers within 6 hours before presentation and if they are younger than 18 and greater than 55 years old.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of pain. Timepoint: before treatment initiation and sequentially at 20,40,60 minutes. Method of measurement: Visual Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart Rate. Timepoint: before treatment initiation and sequentially at 20,40,60 minutes. Method of measurement: Radial Pulse.;Blood pressure. Timepoint: before treatment initiation and sequentially at 20,40,60 minutes. Method of measurement: sphygmomanometer.;Body temprature. Timepoint: before treatment initiation and sequentially at 20,40,60 minutes. Method of measurement: Thermometer(axillary).;Respiratory rate. Timepoint: before treatment initiation and sequentially at 20,40,60 minutes. Method of measurement: Physical examination.;Size of renal calculi. Timepoint: after pain relief. Method of measurement: imaging findings.;Location of renal calculi. Timepoint: after pain relief. Method of measurement: imaging findings.;Paracetamol side effects. Timepoint: in all the time in care. Method of measurement: questionnaire and physical examination.;Ketorolac side effects. Timepoint: in all the time in care. Method of measurement: questionnaire and physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Davood Arab
Semnan University of Medical Sciences
Outcome results
None listed