Comparison between the clinical efficacy of Intravenous Fentanyl and Ketorolac in relieving renal colic pain

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150902023855N3

Enrollment

110

Registered

2020-07-14

Start date

2020-06-03

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Renal Colic. N20.2

Interventions

Intervention 1: Intervention group 1: patients will receive 0.1mg intravenous Fentanyl (Darou Pakhsh Pharmaceutical company) infused in 100 ml normal saline within 10 minutes. Intervention 2: Interven

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Patients with a history of unilateral abdominal or flank pain that the treating emergency physicians suspect to be renal colic Ultrasonography or CT Scan or intravenous pyelography (IVP) findings consistent with the diagnosis of renal stone Stone excretion

Exclusion criteria

Exclusion criteria: Visual Analog Scale (VAS)=3 History of peptic ulcer disease History of asthma History of bleeding disorder Using of oral anticoagulant Impaired renal or hepatic function Hypersensitivity to Aspirin or NSAID or Fentanyl Pregnant and breast-feeding women Received Sedative,Antipsychotic,MAO-I, painkillers within 6 hours before Younger than 18 and greater than 55 years old

Design outcomes

Primary

Measure	Time frame
Pain level. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Visual Analogue Scale.	—

Secondary

Measure	Time frame
Heart rate. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Radial puls.;Blood pressure. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Sphygmomanometer.;Body temperature. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Thermometer(axillary).;Respiratory rate. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Physical exam.;Fentanyl side effects. Timepoint: In all the time in care. Method of measurement: Questionnaire and physical examination.;Ketorolac side effect. Timepoint: In all the time in care. Method of measurement: Questionnaire and physical examination.	—

Measure

Time frame

Heart rate. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Radial puls.;Blood pressure. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Sphygmomanometer.;Body temperature. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Thermometer(axillary).;Respiratory rate. Timepoint: Before treatment initiation and sequentially at 20, 40, 60 minutes. Method of measurement: Physical exam.;Fentanyl side effects. Timepoint: In all the time in care. Method of measurement: Questionnaire and physical examination.;Ketorolac side effect. Timepoint: In all the time in care. Method of measurement: Questionnaire and physical examination.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Davood Arab

Semnan University of Medical Sciences

drdavoodarab@semums.ac.ir+98 23 3343 7830

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026