Condition 1: Major depression. Condition 2: Major depression. Mild depressive episode Moderate depressive episode
Conditions
Interventions
Intervention 1: The intervention group clinical citalopram 40 mg for 6 weeks plus allopurinol 300 mg daily receive. Intervention 2: Clinical citalopram 40 mg daily for 6 weeks plus a control group tha
Treatment - Drugs
The intervention group clinical citalopram 40 mg for 6 weeks plus allopurinol 300 mg daily receive.
Clinical citalopram 40 mg daily for 6 weeks plus a control group that received placebo.
Sponsors
Arak University of Medical Sceinces
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 18 to 65 years, diagnosed with major depression based on clinical interviews and diagnostic criteria for DSM V; normal blood levels of uric acid and liver enzymes (ALT, AST) Exclusion criteria: Serious psychiatric disorders, personality disorders; Taking several drugs simultaneously; severe physical illness; Sensitivity to allopurinol
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Square. Timepoint: Before the intervention, 4 to 6 weeks, end of study. Method of measurement: Hamilton questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ranjbaran Farideh
Arak University of Medical sceinces
Outcome results
None listed