Effect of Capparis spinosa root cream with Phototherapy in Patients with Vitiligo

The efficacy of Capparis spinosa root cream plus narrow-band ultraviolet B in the treatment of vitiligo in patients referring to dermatology clinic of Shahid Faghihi Hospital: A double-blind, placebo-controlled clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150825023753N7

Enrollment

Registered

2018-05-25

Start date

2018-05-22

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitiligo. Vitiligo

Interventions

Intervention 1: Intervention group: Topical use of Capparis spinosa extract cream on vitiligo lesions three times a day. Intervention 2: Control group: Topical use of placebo extract cream on vitilig

Eligibility

Sex/Gender

All

Age

12 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age of 12 to 65 years Confirmation of vitiligo diagnosis by dermatologist Patient satisfaction to enter the research plan No use of other medications and therapeutic methods from the previous last months The disease is not progressive phase

Exclusion criteria

Exclusion criteria: Pregnant and lactating women Positive history of reaction to Capparis spinosa The presence of other systemic and autoimmune diseases associated with vitiligo Dissatisfaction with the entry into the research plan Patient Hepatitis, AIDS and infectious diseases and skin cancers

Design outcomes

Primary

Measure	Time frame
VASI Score. Timepoint: once every two weeks. Method of measurement: Vitiligo Area Scoring Index checklist.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Mahdi Parvizi

Shiraz University of Medical Sciences

mmparvizi@gmail.com+98 71 3212 5592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026