Skip to content

Effect of Citrullus colocynthis on neurological symptoms caused by cancer

Evaluation of topical Citrullus colocynthis fruit oil efficacy in treatment of chemotherapy-induced peripheral neuropathy in cancer patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150825023753N5
Enrollment
50
Registered
2018-02-16
Start date
2017-10-23
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chemotherapy-induced peripheral neuropathy. Drug-induced polyneuropathy

Interventions

Intervention 1: Intervention group: Topical use of Citrullus colocynthis fruit oil product, twice daily (morning and night), all four lower and upper extremities, from ankle to toe, and from wrist to

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with cancer who have symptoms of peripheral neuropathy The duration between the patient's visit for enrolling to the study and the last time receiving chemotherapy is at most two month A neurologist will recognize that their neuropathy is due to chemotherapy Age between 18-80 years old

Exclusion criteria

Exclusion criteria: Patients with diabetes mellitus Patients with brain metastasis Patients with carpal tunnel syndrome Unwilling to participate in the study Creating acute psychological symptoms such as depression (such as taking medication) Deficiency or high levels of vitamin B6 (according to your doctor's interview and examination) Any positive history of allergic reaction or complications due to uising Citrullus colocynthis Patients with serious illness

Design outcomes

Primary

MeasureTime frame
Chemotherapy Induced Peripheral Neuropathy score. Timepoint: Before and after. Method of measurement: Using of Chemotherapy Induced Peripheral Neuropathy Assessment Tool (CIPNAT).;Symptoms and concerns associated specifically with chemotherapy-induced neuropathy score. Timepoint: Before and after. Method of measurement: Using Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity (Fact/GOG-Ntx) questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ghazaleh Heydarirad

Shahid Beheshti University of Medical Sciences

ghazalrad@yahoo.com+98 21 8877 6027

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026