Acne. Acne vulgaris
Conditions
Interventions
Intervention 1: Intervention group: The first group is treated with dexpanthenol 500 mg ampoule manufactured by Actover pharmaceutical company, one intramuscular injection and adapalene gel per week.
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to 40 Years
Inclusion criteria
Inclusion criteria: Patients with mild to moderate acne Patients have not received any systemic treatment in the last one month and have not received any local treatment in the last two weeks Married women who agree to use physical methods of contraception such as condoms and IUDs during the study
Exclusion criteria
Exclusion criteria: Pregnant and lactating women Patients with polycystic ovary syndrome Lack of consent to continue studying Use of herbal medicines History of allergy to the studied drug Allergy to adapalene gel Inability to visit regularly to check response to treatment Patients with severe acne Existence of systemic disease including kidney and liver problems Current use of dietary supplements for skin health
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acne severity. Timepoint: Base line, first month, second month. Method of measurement: Acne severity GAGS (Global Acne Grading System). | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life of the patients. Timepoint: Base line, first month, second month. Method of measurement: Dermatology Quality of Life Index.;Acne count. Timepoint: Base line, first month, second month. Method of measurement: Counting the acne lesions. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFahimeh Mohammadi, MD
Shiraz University of Medical Sciences
Outcome results
None listed