Melasma. Chloasma
Conditions
Interventions
Intervention 1: Intervention group: Patients in the intervention group will receive 8 grams of oily capsule containing safflower seed oil (manufactured by Barij Company) orally, daily. Also, patients
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Diagnosis of melasma by a dermatologist The patient is bound to cooperate for regular use of the studied drug and refer at the appointed time Having informed and written consent to participate in the study Satisfaction with not using out-of-protocol therapies
Exclusion criteria
Exclusion criteria: Pregnant and lactating women Individuals with other organ disorders (cancers, liver, kidney) History of hypersensitivity reaction to safflower seeds 39/5000Patient dissatisfaction to continue the project for any reason Individuals with diabetes Taking skin lightening medications in the last two weeks Taking hormonal contraceptives and other medications that cause melasma Taking anticoagulants (aspirin, Plavix, warfarin) Individuals with coagulation diseases History of hypersensitivity to safflower seeds
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of melasma discoloration. Timepoint: Measurements are taken at the start of the study, one month and two months after the start of the study. Method of measurement: Using Visioface 1000D and The Melasma Area and Severity Index (MASI). | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life of patients with melasma. Timepoint: This variable is measured at the beginning of the study and two months later. Method of measurement: The Melasma Quality of Life scale (MELASQOL). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mohammad Mahdi Parvizi
Shiraz University of Medical Sciences
Outcome results
None listed