Efficacy of topical formulation of Henna in itching sensation and wound healing in patients with epidermolysis bullosa

The pilot study of efficacy of topical formulation of Henna (Lawsonia inermis)1% in itching sensation and wound healing in patients with epidermolysis bullosa: a non randomized open clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150825023753N14

Enrollment

Registered

2019-08-31

Start date

2018-09-23

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epidermolysis Bullosa Dystrophica. Epidermolysis bullosa dystrophica

Interventions

Intervention group: Intervention group includes patients older than 5 years with Epidermolysis Bullosa who received topical product containing 1% henna extract. is that the patient uses 0.5 grams of c

Eligibility

Sex/Gender

All

Age

5 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with Epidermolysis Bullosa Age over 5 years old Patient or his/her parent's consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients younger than 5 years old Patients or their parents not consenting to participate in the study Positive history of allergic to Henna Patients with G6PD deficiency (Glucose-6-phosphate dehydrogenase deficiency)

Design outcomes

Primary

Measure	Time frame
Itching score. Timepoint: Once a week until 1 month. Method of measurement: Visual Analogue Scale (VAS).;Percentage of wound healing. Timepoint: Percentage of wound healing. Method of measurement: Clinical global impression of improvement.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Mahdi Parvizi

Shiraz University of Medical Sciences

mmparvizi@gmail.com+98 71 3235 1087

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026