The effect of phototherapy and oral Simvastatin in treatment of vitiligo

A comparative study on the therapeutic effect of combined phototherapy and oral Simvastatin with phototherapy alone in patients with vitiligo

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150825023753N11

Enrollment

Registered

2019-03-30

Start date

2016-07-22

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitiligo. Vitiligo

Interventions

Intervention 1: Intervention group: The initial dose of phothotherapy used in every patient is 100 mJ/cm2 and the energy is increased by 10 mJ/cm2 after every dose. The number of treatment sessions of

Eligibility

Sex/Gender

All

Age

14 Years to No maximum

Inclusion criteria

Inclusion criteria: The patients with vitiligo Age above 14 years old

Exclusion criteria

Exclusion criteria: Patients with systemic diseases Patients who use other therapeutic methods except light therapy Patients with any liver disease Patients with any kidney disease Pregnant and lactating women History of allergy to phototherapy Taking medication that has interactions with simvastatin

Design outcomes

Primary

Measure	Time frame
The amount of melanin pigment in the skin. Timepoint: Assessment the amount of melanin pigment at the start of the study and at the end of the first, second, third and fourths month after beginning the treatment. Method of measurement: Vitiligo Area Scoring Index (VASI Score).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ladan Dastgheib

Shiraz University of Medical Sciences

dastghl@sums.ac.ir+98 71 3212 5592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026