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Effect of granulocyte colony stimulating factor in ART treatment

Effect of granulocyte colony stimulating factor (G-CSF) on IVF outcome and pregnancy rates.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201508236420N13
Enrollment
100
Registered
2015-11-07
Start date
2015-03-21
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Complication associated with artificial fertilization, unspecified

Interventions

Intervention 1: In intervention group in oocyte retrieval day, 300 microgram G-CSF ampoul infused in endometrial cavity with IUI catheter immediately after retrieval. Intervention 2: in control group

Sponsors

Vice Chancellor for research of Shahid Sadoughi University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: infertile women candidate for IVF normal endometrial thickness age18-40 years old

Exclusion criteria

Exclusion criteria: repeated implantation failure endocrine disorders severe endometriosis congenital or acquired uterine anomaly renal disease sickle cell disease malignancy history upper respiratory tract infection pneumonia chronic neutropenia

Design outcomes

Primary

MeasureTime frame
Chemical pregnancy. Timepoint: 14 days after embryo transfer. Method of measurement: serum ßhCG.

Secondary

MeasureTime frame
Ongoing pregnancy. Timepoint: 10 weeks after embryo transfer. Method of measurement: sonography.;Abortion. Timepoint: 18 weeks after embryo transfer. Method of measurement: sonography.;Clinical pregnancy. Timepoint: 3 weeks after positive BHCG. Method of measurement: sonography.;Implantation. Timepoint: 3 weeks after positive BHCG. Method of measurement: assessed by the number of gestational sacs per number of transferred embryos.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Eftekhar

Sadoughi University of Medical Science ,Yazd

eftekharmaryam@yahoo.com+98 35 3824 7085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026