Breast cancer. Malignant neoplasm of breast
Conditions
Interventions
Intervention 1: Intervention group: supplement therapy with a soft-gel of 50000 IU cholecalciferol(vitamin D) per week for 8 weeks the duration of intervention. The soft-gel produced by Zahravi pharm
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: The range of body mass index (BMI) is 20 to 35 kg/m2 30 – 65 years old histopathologic confirmed breast malignancy histopathologic grades of 2 and 3 tendency to participate in study completed questionnaire tamoxifen consumption
Exclusion criteria
Exclusion criteria: Being at clinical stage 4 pregnancy lactation acute renal or liver failure using antiepileptic medications and contraceptive drugs history of hormonal related diseases (such as diabetes, hyperthyroidism and poly cystic ovary syndrome) nausea vomiting headache vertigo
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum levels of angiopoietin-2 and VEGF-A. Timepoint: Baseline and 8 week after baseline. Method of measurement: ELISA. | — |
Secondary
| Measure | Time frame |
|---|---|
| Anthropometric parameters. Timepoint: Baseline and 8 week after baseline. Method of measurement: Waist circumference, body mass index (kg/m2), and waist to hip ratio. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaeed Pirouzpanah
Tabriz University of Medical Sciences
Outcome results
None listed