Condition 1: Acne Scar. Condition 2: Wrinkle. Scar conditions and fibrosis of skin Disorder of skin and subcutaneous tissue, unspecified
Conditions
Interventions
3 sessions of intradermal injection of autologous cultured fibroblast 0.1 ml along each cm with 4 weeks intervals.
3 sessions of intradermal injection of autologous cultured fibroblast 0.1 ml along each cm with 4 weeks intervals
Sponsors
Royan Institute
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Age>18 years; facial wrinkle or acne scar of at-least 2 out 7; Ability to sign informed consent. Exclusion Criteria: Known allergy or sensitivity to collagen fillers; history of soft tissue augmentation to the area during last 6 months; autologous fat transfer in the last 6 months; facial Kaposi sarcoma; active skin diseases or inflammation of the treatment area; Silicon injection in treatment site; pregnancy or lactating; systemic immunosuppressive or steroid drugs during past 6 months; current anticoagulant therapy; disease of connective tissue; malignant disease; Positive HIV, HBV, HCV
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease in scar and wrinkle score. Timepoint: 2, 6 and 12 months after cell injection. Method of measurement: Based on evaluator assessment score according to standardized 7-point grading. | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety. Timepoint: 2, 6 and 12 months after cell injection. Method of measurement: Assessments based on evaluator and subject. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Bajouri
Royan Institute
Outcome results
None listed