Comparison postoperative pain of mechanical versus alcohol assisted epithelial removal before PRK

Comparison postoperative pain of mechanical versus alcohol assisted epithelial removal before PRK in a double blind clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015081713567N10

Enrollment

120

Registered

2017-08-19

Start date

2015-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myopia, hyperopia. mild or no visual impairment, binocular

Interventions

Intervention 1: Intervention Group: One eye of patient will be operated in mechanical surgery way by method of PRK. Intervention 2: Control Group: Another Eye of patient will be PRK operated by the me

Treatment - Surgery

Intervention Group: One eye of patient will be operated in mechanical surgery way by method of PRK.

Control Group: Another Eye of patient will be PRK operated by the method of using alcohol.

Eligibility

Sex/Gender

All

Age

19 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 19 to 60 years old; refraction stability of at least 1 year Exclusion criteria: Keratoconus, Herpetic keratitis, Corneal dystrophy, Cataract, Glaucoma, Dry eye, Uveitis, Blepharitis, diabetes, Pregnancy, Breast feeding, Auto immune disease, Immunodeficiency, History of keloid formation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 1st postoperative day. Method of measurement: Questionnaire.;Photophobia. Timepoint: 1st postoperative day. Method of measurement: Questionnaire.;Epiphora. Timepoint: 1st postoperative day. Method of measurement: Questionnaire.;Foregin body sensation. Timepoint: 1st postoperative day. Method of measurement: Questionnaire.;Blurred vision. Timepoint: 1st postoperative day. Method of measurement: Questionnaire.	—

Measure

Time frame

Pain. Timepoint: 1st postoperative day. Method of measurement: Questionnaire.;Photophobia. Timepoint: 1st postoperative day. Method of measurement: Questionnaire.;Epiphora. Timepoint: 1st postoperative day. Method of measurement: Questionnaire.;Foregin body sensation. Timepoint: 1st postoperative day. Method of measurement: Questionnaire.;Blurred vision. Timepoint: 1st postoperative day. Method of measurement: Questionnaire.

—

Secondary

Measure	Time frame
Satisfaction. Timepoint: 1st postoperative day. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehrdad Mohammadpour

Tehran University of Medical Sciences

mohammadpour_m@sina.tums.ac.ir+98 21 5542 1006

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026