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The effect of hydrodissection on antimullerian hormone (AMH) in laparoscopic endometrioma surgery

Evaluation of the effect of hydrodissection with and without vasopressin on antimullerian hormone (AMH) in comparison with the usual method in laparoscopic endometrioma surgery: a double-blind clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150817023666N13
Enrollment
15
Registered
2021-04-20
Start date
2021-02-19
Completion date
Unknown
Last updated
2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Women with endometrioma ovarian cysts.

Interventions

Intervention 1: Intervention group 1: Laparoscopic cystectomy for ovarian cyst surgery is performed by hydro dissection (50-70 ml of normal saline) in which hydrodissection is injected in several poin
Hydrodissection method with vasopressin (Durvana company) in the intervention group, before starting to remove the wall of the cyst 3 ml, contains 0.3 units of an ampoule called vasopressin (Hypress)

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Women of childbearing age are 18 to 35 years old. With endometrioma ovarian cysts less than 10 cm. Has unilateral ovarian cysts with a diameter of 4 to 10 cm that are confirmed by ultrasound. Have a body mass index between 19 and 30. Have not received hormonal drugs, especially GnRH agonists, in the last 3 months.

Exclusion criteria

Exclusion criteria: Patients have unilateral ovarian cysts 4 -10 cm in diameter, which are confirmed by ultrasound sonography.

Design outcomes

Primary

MeasureTime frame
Antimullerian Hormone changes in patients. Timepoint: Mean levels of Antimullerian Hormone in all patients before and after laparoscopic cystectomy. Method of measurement: Questionnaire and patient file.;Hemoglobin changes in patients. Timepoint: Mean levels of hemoglobin in all patients before and after laparoscopic cystectomy. Method of measurement: Questionnaire and patient file.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Abolfazl Mehdizadeh Kashi

Iran University of Medical Sciences

mehdizadeh.a@iums.ac.ir+98 21 6650 9283

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026