Metabolic syndrom. Metabolic syndrome
Conditions
Interventions
Intervention 1: Intervention group: Each capsule contains 80 mg nanomicielles curcumin. Use once a day for 12 weeks. Intervention 2: Control group: Each capsule contains yellow colour(E104) and lecit
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Tendency for participation Age between 18-70 years old BMI between 25-40 kg/m2 Having metabolic syndrome according to the NCEP ATP III definition(if patient have three or more of the following five criteria): waist circumference over 120 cm (men) or 89 cm (women), blood pressure over 130/85 mmHg, fasting triglyceride (TG) level over 150 mg/dl, fasting high-density lipoprotein (HDL) cholesterol level less than 40 mg/dl (men) or 50 mg/dl (women) and fasting blood sugar over 100 mg/dl.
Exclusion criteria
Exclusion criteria: Pregnancy Lactation Use insulin injection Thyroid disorder Henal disease Having unusual diet during 3 last month Use weight loss and fat burner drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Homeostatic model assessment of insulin resistance(HOMA-IR). Timepoint: Baseline and end of the study. Method of measurement: Calculation :(glucose×Insulin)/22.5.;Homeostatic model assessment of B-cell function(HOMA-B). Timepoint: Baseline and end of the study. Method of measurement: Calculation.;Hba1c. Timepoint: Baseline and end of the study. Method of measurement: ion-exchange chromatography.;Serum glucose. Timepoint: Baseline and end of the study. Method of measurement: Colorimetric analysis method.;Serum insulin. Timepoint: Baseline and end of the study. Method of measurement: ELISA method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZohre Bateni
Shahid Beheshti University of Medical Sciences
Outcome results
None listed