Fracture of Lower Limb. Fracture of lower limb, level unspecified
Conditions
Interventions
After the surgery and following transference of the patients to the recovery section, 25 mg pethidine was injected intravenously..
Treatment - Drugs
After the surgery and following transference of the patients to the recovery section, 25 mg pethidine was injected intravenously.
Sponsors
Vice Chancellor for Research Affairs, Islamic Azad University, Pharmaceutical Sciences Branch
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria include: Age between 18 and 35 years; Not having substance abuse; Having physical and mental health; Having post-operative pain; Having full consciousness; Being classified as class I patients (according to the American society of anesthesiologists physical status classification). Exclusion Criteria include: Pregnancy; Lactation; Having seizures; Having psychiatric disorders; Undergoing emergency surgical operations; Having abnormal paraclinical tests.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of pain intensity. Timepoint: 5, 30, 60 and 180 minutes after drug injection. Method of measurement: Based on Visual Analogue Scale (VAS).;Measuring blood levels of pethidine. Timepoint: 5, 30, 60 and 180 minutes after injection. Method of measurement: with HPLC Method. | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse drug reactions. Timepoint: 5, 30, 60 and 180 minutes after injection of the drug. Method of measurement: Observation and clinical studies. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Farshad Hashemian
Islamic Azad University, Pharmaceutical Sciences Branch, Faculty of Pharmacy
Outcome results
None listed