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Comparison of analgesic efficacy of celecoxib and acetaminophen in pediatric Tonsillectomy

Comparison of analgesic efficacy of celecoxib and acetaminophen in pediatric Tonsillectomy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015080919470N29
Enrollment
200
Registered
2016-12-27
Start date
2015-04-30
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tonsilectomy. Chronic disease of tonsils and adenoid

Interventions

Intervention 1: Intervention group 1: The first dose of acetaminophen after discharge will consist of oral suspension 120mg/5 ml, 400 mg at 4 hours after tonsillectomy and then every 6 hours for seven
Treatment - Drugs
Intervention group 1: The first dose of acetaminophen after discharge will consist of oral suspension 120mg/5 ml, 400 mg at 4 hours after tonsillectomy and then every 6 hours for seven days.
Intervention group 2: The first dose of celecoxib after discharge will consist of oral suspension 100mg/5 ml, (50mg for children under 25 kg and100mg for upper) at 4 hours after tonsillectomy and then

Sponsors

Vice Chancellor for Research, Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 15 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 3 - 15 years old children; no growth anomalies; physical or psychological problems; living nearby the hospital; at least one of the parents should have high school education. Exclusion criteria: history of allergy to celecoxib or other NSAIDs; asthma; kidney or liver dysfunction or a hemorrhagic diathesis and sulphonamide allergy; social reasons.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain score intensity. Timepoint: 4 times a day; before breakfast, lunch and dinner and sleeping. Two weeks after Tonsillectomy. Method of measurement: Visual Analog Scale (VAS).

Secondary

MeasureTime frame
Bleeding. Timepoint: Daily. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBahar Nouri Rahmt Abadi

Shiraz University of Medical Sciences

baharnoori64@yahoo.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026