Hemodynamic changes.
Conditions
Interventions
Intervention 1: In 1th intervention group 0.75 mg/kg lidocaine 4% will sprayed to the larynx and gloat, 2 minutes before intubation and the same dose will sprayed at intubation time. Intervention 2: I
Treatment - Drugs
In 1th intervention group 0.75 mg/kg lidocaine 4% will sprayed to the larynx and gloat, 2 minutes before intubation and the same dose will sprayed at intubation time.
In 2th intervention group 0.75 mg/kg lidocaine 2% was injected intravenously, 2 minutes before intubation and the same dose will injected at intubation time.
The main drugs used in the control group and of any type of lidocaine is not used.
Sponsors
Arak University of Medical Sceinces
Eligibility
Sex/Gender
All
Age
25 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients between 25 to 40 years old admitted to the ICU and indication for endotracheal intubation; patients without underlying disease such as diabetes, hypertension, cardiovascular disease, kidney and liver diseases, respiratory diseases, recent respiratory infection; patients classified for 1 or 2 ASA; obtaining informed consent from attendant patients for the study. Exclusion criteria: patients who had a history of lidocaine hypersensitivity; pregnancy and lactation
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic blood pressure. Timepoint: at intubation time and 2 and 5 minutes after Intubation. Method of measurement: mmhg with mercury sphygmomanometer.;Diastolic blood pressure. Timepoint: at intubation time and 2 and 5 minutes after Intubation. Method of measurement: mmhg with mercury sphygmomanometer.;Heart rate. Timepoint: at intubation time and 2 and 5 minutes after Intubation. Method of measurement: heart rate per minute.;Mean arterial pressure. Timepoint: at intubation time and 2 and 5 minutes after Intubation. Method of measurement: mmhg with mercury sphygmomanometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Abolfazl Jokar
Arak University of Medical sceinces
Outcome results
None listed