Effect of pretreatment nicorandil VS atorvastatin on contrast-Induced nephropathy in patients with normal renal function

Preventive effect of pretreatment with Intravenous nicorandil VS atorvastatin on contrast-Induced nephropathy in patients with normal renal function undergoing coronary angiography

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150808023559N22

Enrollment

128

Registered

2020-05-20

Start date

2020-07-22

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nephropathy. Nephropathy induced by other drugs, medicaments and biological substances

Interventions

Intervention 1: Intervention group: Atorvastatin 80 mg will be used for 3 days before and two days after angiography. Intervention 2: Control group: 10 mg of Nicorandil will be taken daily before 30 m

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Coronary angiography Normal renal function

Exclusion criteria

Exclusion criteria: Sensitivity to contrast agent

Design outcomes

Primary

Measure	Time frame
Nephropathy due to contrast subjects. Timepoint: 24 and 48 hours after angiography. Method of measurement: Measurement of serum creatinine.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Atigi

Ardabil University of Medical Sciences

elham.atighi@yahoo.com+98 45 3325 1410

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026