Skip to content

Comparison of ketorolac and paracetamol on post operative pain in orthopedic surgery

Comparison of the effect of ketorolac and paracetamol on post operative pain in patients undergoing lower limb orthopedic surgery

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015080712007N3
Enrollment
96
Registered
2015-08-23
Start date
2015-01-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pain. Pain in limb

Interventions

Intervention 1: One group will receive 1 gr intravenous paracetamol in 500 cc normal saline 10 minutes before induction of anesthesia. Intervention 2: Second group will receive 30 mg intravenous ketor
Treatment - Drugs
Placebo
One group will receive 1 gr intravenous paracetamol in 500 cc normal saline 10 minutes before induction of anesthesia
Second group will receive 30 mg intravenous ketorolac in 500 cc normal saline
In control group 500 ml normal saline will be given 10 minutes before induction of anesthesia

Sponsors

Vice Chancellor for research of Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ASA classification of I and II; age 18 to 65 years. Exclusion criteria: opioids and narcotics abuse for a long time; steroids consumption; pregnancy; history of heart, liver and kidney failure; coagulation disorders; uncontrolled hypertension; endocrine disorders (diabetes); BMI higher than 40; alcoholism; heart rate less than 40 b/m; surgical procedure up to 2 hours; asthma; GI bleeding.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 45 minutes after consciousness. Method of measurement: VAS (visual analogue scale).

Secondary

MeasureTime frame
Heart rate. Timepoint: every 15 minutes. Method of measurement: automatic monitoring device.;Blood pressure. Timepoint: Every 15 minutes. Method of measurement: Automatic monitoring device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAnis Bahrami

Kerman University of Medical Sciences

anis_bahrami@yahoo.com+98 34 1223 5011

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026