Prophylactic administration of intravenous Paracetamol for control of shivering during and post cesarean section with spinal anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015080710765N7

Enrollment

100

Registered

2015-09-15

Start date

2015-08-08

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Intra and post spinal anesthesia shivering. Condition 2: complications of anaesthesia. Hypothermia, not associated with low enviromental temperature Other complications of anesthesia

Interventions

Intervention 1: Intervention group: in this group paracetamol 1000mg in 100 cc normal saline was infused during 15 -20 min after neonatal delivery for prevention of intra and post-operative shiverin

Treatment - Drugs

Placebo

Intervention group: in this group paracetamol 1000mg in 100 cc normal saline was infused during 15 -20 min after neonatal delivery for prevention of intra and post-operative shivering .

Control group: in this group normal saline iv in same volume intervention group was infused as placebo at 15-20 min after neonatal delivery .

Eligibility

Sex/Gender

Female

Age

16 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: pregnant womenaged between 16 to 45 years old candidate for elective cesarean section with spinal anesthesia; ASA physical class I or II with informed consent for spinal anesthesia. Exclusion criteria: patients with ASA physical class III or higher; contraindication for administration of NSAIDS and paracetamol; peptic ulcer; coagulopathy; renal failure;hepatic failure; fever; any contraindication for performing spinal anesthesia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity of perioperative and postoperative shivering. Timepoint: In recovery every 15 minutes until discharge from recovery. Method of measurement: Crossly and Mahjon five-point scoring system.;Incidence of intra and post spinal anesthesia shivering. Timepoint: During of surgery and in the recovery room. Method of measurement: visual.	—

Secondary

Measure	Time frame
Need to drug for treatment of shivering. Timepoint: During surgery and in recovery room. Method of measurement: Dose of drug.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSousan Rasouli

Tabtiz University of Medical Sciences

rasooli_s@yahoo.com+98 41 3553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026