Ectopic pregnancy. Ectopic pregnancy, unspecified
Conditions
Interventions
Intervention 1: In single dose group
50mg/m2 methotrexate was administered in day 0. Intervention 2: In the double dose group
patients received two doses (50mg/m2 methotrexate) in day 0 and 4.
Treatment - Drugs
In single dose group
50mg/m2 methotrexate was administered in day 0
In the double dose group
patients received two doses (50mg/m2 methotrexate) in day 0 and 4
Sponsors
Ahwaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion criteria: stable hemodynamic condition; low free fluid intrapritoneal on ultrasound; BHCG less than 15000 mU/mL; no history of liver or renal disease or blood dyscrasia; no breastfeeding and patient satisfaction. Exclusion criteria: unwillingness to continue participation in the study; unstable hemodinamic condition.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The overall success(15% reduction in ß-HCG level ). Timepoint: At days: 4 and 7. Method of measurement: Lab test. | — |
Secondary
| Measure | Time frame |
|---|---|
| The time BHCG reached 200 mU/mL. Timepoint: daily. Method of measurement: Lab test.;Side effects. Timepoint: 7 days after treetment. Method of measurement: If liver trans aminase increased 1.5 times more than normal, or creatinine increased to 1.5mg/dL, WBCs decreased to 2000 or platelets declined fewer than 100000, these were assumed as drug complications.;The rate of surgery. Timepoint: During the follow-up period. Method of measurement: If the rupture of fallopian tube has happened, patient underwent the immediate surgery. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSara Safyari
Ahwaz Jondishapur University of Medical Sciences
Outcome results
None listed