Advantages and Disadvantages of Dexamethasone Administration after Tonsillectomy in Children

Determination of Dexamethasone Effects on Postoperative Pain, Nausea and Vomiting, Bleeding, Odynophagia, Voice change, Halitosis, Otalgia after Tonsillectomy in Children Aged 4 to 10 Years

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015080522889N2

Enrollment

100

Registered

2015-09-09

Start date

2011-12-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertrophy of tonsils and adenoids. Hypertrophy of tonsils with hypertrophy of adenoids

Interventions

Intervention 1: In interventional group: using dexamethasone 0.1 mg/kg after adenotonsilectomy (in ward). Intervention 2: In control group: using ringer serum after adenotonsilectomy (in ward).

Treatment - Drugs

In interventional group: using dexamethasone 0.1 mg/kg after adenotonsilectomy (in ward)

In control group: using ringer serum after adenotonsilectomy (in ward)

Eligibility

Sex/Gender

All

Age

4 Years to 10 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 4 to 10 years old children candidate for adenotonsilectomy in Khalili hospital between February 2011 and March 2013; Completing consent form; Completing demographic information and questionnaire Exclusion criteria: Patient’s with history of convulsion; prematurity; allergy or hypersensitivity to dexamethasone; syndromic disease (e.g. Down syndrome) ; coagulation disorder; systemic disease; developmental problems; congenital heart disease; nutritional deficiencies like SDP and G6PD; patient with poor follow up.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Bleeding. Timepoint: 1 day and during 7 days after surgery. Method of measurement: physical examination and questionnaire.;Nausea and vomiting. Timepoint: 1 day and during 7 days after surgery. Method of measurement: physical examination and questionnaire.;Odynophagia. Timepoint: 1 day and during 7 days after surgery. Method of measurement: physical examination and questionnaire.;Voice change. Timepoint: 1 day and during 7 days after surgery. Method of measurement: physical examination and questionnaire.;Acetaminophen intake. Timepoint: during 7 days after surgery. Method of measurement: physical examination and questionnaire.;Halitosis. Timepoint: during 7 days after surgery. Method of measurement: physical examination and questionnaire.;Otalgia. Timepoint: during 7 days after surgery. Method of measurement: physical examination and questionnaire.	—

Measure

Time frame

Bleeding. Timepoint: 1 day and during 7 days after surgery. Method of measurement: physical examination and questionnaire.;Nausea and vomiting. Timepoint: 1 day and during 7 days after surgery. Method of measurement: physical examination and questionnaire.;Odynophagia. Timepoint: 1 day and during 7 days after surgery. Method of measurement: physical examination and questionnaire.;Voice change. Timepoint: 1 day and during 7 days after surgery. Method of measurement: physical examination and questionnaire.;Acetaminophen intake. Timepoint: during 7 days after surgery. Method of measurement: physical examination and questionnaire.;Halitosis. Timepoint: during 7 days after surgery. Method of measurement: physical examination and questionnaire.;Otalgia. Timepoint: during 7 days after surgery. Method of measurement: physical examination and questionnaire.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Saeid Pourseirafi

Shiraz University of Medical Sciences

dr.s.pourseirafi@gmail.compourseirafi@sums.ac.ir+98 31 4524 8966

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026