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The effects of Opium Tincture in the control of clinical signs associated with methamphetamine

Comparison of Haloperidol and Opium Tincture in the control of clinical signs associated with methamphetamine

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015080223470N1
Enrollment
70
Registered
2015-09-11
Start date
2015-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Methamphetamin dependency. Psychostimulants with abuse potential

Interventions

Intervention 1: Standard group give Haloperidol 1mg during 1week, than 1mg/bid during 3 week. Intervention 2: Intervention group give Opium tincture 14cc/day during 2week, than is low 1cc every 4 days
Treatment - Drugs
Standard group give Haloperidol 1mg during 1week, than 1mg/bid during 3 week.
Intervention group give Opium tincture 14cc/day during 2week, than is low 1cc every 4 days.

Sponsors

Vice Chancellor for Research, University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Dependence on methamphetamine (more than 10 times the regular use of methamphetamine or 10 days); Urine tests positive for methamphetamine; Age 18-65 years; Independence and no use of drugs or other addictive drugs at the time of presentation; Complete the consent form; To track patient; Exclusion criteria: Unwillingness person to continue treatment; Patient self-medication or participate in another study; Other addictive drugs or alcohol or drug use during the study period; Non-compliance with medication orders during the study; Coming out of treatment (imprisonment, death, ...); Any behavior that resulted in dismissal laws rehab clinic patient; There are other mental disorders that require treatment or the risk of suicide; Significant diseases of the Thyroid, Kidney, Liver, Gastrointestinal or Cardiovascular; History of diabetes or Heart attack, Seizures, Glaucoma, Tick, Tardive dyskinesia; Female without adequate contraception pregnancy or lactation; Tincture of opium abusers; A history of allergy to Haloperidol; Simultaneous treatment with antipsychotics or mood stabilizers or CYP 2D6 inhibitors Contains: Amiodarone, Bupropion, Celecoxib, Cimetidine, Chlorpromazine, Clomipramine, Fluoxetine, Haloperidol, Methadone, Moclobemide, Paroxetine, Quinidine, Ritonavir, Sertraline, Terbinafine and Thioridazine; So dangerous side effects of medications or the patient is intolerable.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sleep condition improve. Timepoint: Befor and during and after invetervention. Method of measurement: Beck questionnaire.;Psychotic reaction. Timepoint: Befor and during and after invetervention. Method of measurement: Beck questionnaire and Psychological exam.;Craving. Timepoint: Befor and during and after invetervention. Method of measurement: Psychological exam.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. mohammad fazli

Arak University of Medical Sciences

mohammadfazli69@gmail.com+98 86 4633 2542

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026