Premenstrual syndrome (PMS). Premenstrual tension syndrome
Conditions
Interventions
Intervention 1: Taking two oral capsules in a day (capsule with 8 mg Piperine, and capsule with 50 mg Gelatin) for two weeks in 2 months intervention. Intervention 2: Taking two oral capsules in a day
Treatment - Drugs
Placebo
Taking two oral capsules in a day (capsule with 8 mg Piperine, and capsule with 50 mg Gelatin) for two weeks in 2 months intervention
Taking two oral capsules in a day (capsule with 8 mg Piperine, and capsule with 400 IU vitamin E) for two weeks in 2 months intervention
Taking two oral capsules in a day (capsule with 400 IU vitamin E, and capsule with 50 mg Gelatin) for two weeks in 2 months intervention
Taking two oral capsules of 50 mg Gelatin in a day for two weeks in 2 months intervention
Sponsors
Vice chancellor for research and technology, Iran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age between 18 and 35 years old; being single; being healthy regarding to their self-report and physical examination; having regular menstrual cycles (22-35 days and 2-7 days duration); having premenstrual syndrome (PMS) in 2 past cycles (no sever syndrome); no history of allergy to any food; not taking any medicine; not taking any complements; not smoking, alcohol or drug usage; no history of pregnancy. Exclusion criteria: use of any kind of drug or therapy for symptom relief during the study intervention; side effects during intervention for example allergy; change in diet or physical exercise program during the study; any kind of crisis in participant or her family; not taking capsules more than 7 days in 2 cycles
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Premenstrual syndrome (screening). Timepoint: 2 menstrual cycles. Method of measurement: premenstrual profile 2005 scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Premenstrual syndrome (prevention). Timepoint: During intervention for 2 cycles. Method of measurement: Measure by premenstrual profile 2005 scale, for duration of 2 cycles. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSimin Taavoni
Iran University of Medical Sciences
Outcome results
None listed