Effect of Nystatin therapy versus before treatment in patients with denture stomatitis

Effect of Nystatin therapy versus before treatment in patients with denture stomatitis: a before-after clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201508019014N73

Enrollment

Registered

2015-08-03

Start date

2014-02-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Denture stomatitis. Other forms of stomatitis

Interventions

Treatment with Nystatin 100,000 U three times a day for 14 days.

Treatment - Drugs

Treatment with Nystatin 100,000 U three times a day for 14 days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients without teeth with complete denture. Exclusion criteria: (a) having diabetes mellitus; (b) having immunodeficiency disorder; (c) history of using antibiotic, immunosuppressive drugs, radiotherapy, steroid, or antifungal drugs; (d) being simultaneously affected with other oral diseases such as gingivitis or periodontitis.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Salivary level of IL-10. Timepoint: Before treatment and 14 days after treatment. Method of measurement: Laboratory test.;Salivary level of TNF-a. Timepoint: Before treatment and 14 days after treatment. Method of measurement: Laboratory test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Masoud Rashizadeh

School of Dentistry

rashidzadeh2007@gmail.com+98 81 3838 1086

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026