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Effect of propolis on palatal wound healing and pain management

Evaluation of effect of propolis on palatal wound healing and pain management following harvesting free gingival graft

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015073123425N1
Enrollment
20
Registered
2015-09-01
Start date
2015-10-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gingival graft due to lack of attached gingiva.

Interventions

Intervention 1: in control area, propolis-free oral ointment containing pectin, paraffin and carboxy methyl cellulose is applied over the palatal wound. Intervention 2: in the test area is protected b
Treatment - Drugs
in control area, propolis-free oral ointment containing pectin, paraffin and carboxy methyl cellulose is applied over the palatal wound
in the test area is protected by oral ointment containing 3.6 % propolis.

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: no systemic disease interfere with the wound healing, no cigarette smoking, no allergy to honey Exclusion criteria: patients without cooperation during the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain level. Timepoint: on 1st, 3rd, 7th, 14th and 21st days following the surgery. Method of measurement: visual analogue scale.;Dimensional changes. Timepoint: 7th, 14th, 21st , 30th, 42nd days. Method of measurement: Dimensional changes are evaluated via photographs which are taken at baseline and 7th, 14th, 21st , 30th, 42nd days from palatal wound area. Dimensional changes are evaluated with AutoCAD software and predetermined scale.;Thickness of palatal donor site. Timepoint: 0, 30th and 42nd days. Method of measurement: measured using a sterile kfile #15 on 4 sites of wound area at baseline and 30th, 42nd days and the mean value is recorded.;Color match. Timepoint: 7th, 14th, 21st , 30th, 42nd days. Method of measurement: Color coordination of donor site and adjacent normal tissues are evaluated using Photoshop software.

Secondary

MeasureTime frame
Burning sensation. Timepoint: on 1st, 3rd, 7th, 14th and 21st days. Method of measurement: by asking patients, yes or no.;Number of pain killers consumed. Timepoint: 21st day. Method of measurement: by asking patients.;Number of days patients take the pain killers. Timepoint: on 21st day. Method of measurement: by asking patient.;Bleeding of the wound. Timepoint: on 7th, 14th, and 21st days. Method of measurement: by rubbing the gauze on the wound/ yes or no.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarzaneh Dashkhaneh

Qazvin University of Medical Sciences

farzaneh.d92@gmail.com+98 28 3335 3064

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026