The efficacy of three different anesthetic technique in mandibular molars

Comparing the efficacy of Inferior alveolar nerve block (IANB), IANB along with buccal infiltration and modified intraseptal of Articaine in mandibular molars affected with irreversible pulpitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015073023412N1

Enrollment

Registered

2017-10-15

Start date

2016-02-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulpitis. Diseases of pulp and periapical tissues, irreversible pulpitis

Interventions

Intervention 1: group I: inferior alveolar nerve block (IANB) injection of 1.8 ml of 2% lidocaine with epinephrin 1

100000. Intervention 2: group II: inferior alveolar nerve block injection of 1.8 ml lidocaein 2% with epinephrin 1:100000 and buccal infiltration of 1.8 ml articaine 4% with epinephrin 1:100000. Inter

Treatment - Drugs

group I: inferior alveolar nerve block (IANB) injection of 1.8 ml of 2% lidocaine with epinephrin 1

100000

group II: inferior alveolar nerve block injection of 1.8 ml lidocaein 2% with epinephrin 1:100000 and buccal infiltration of 1.8 ml articaine 4% with epinephrin 1:100000

group III: intraseptal injection of 0.8 ml articaine 4% with epinephrine 1:100000 and bucal infiltration of 1ml articaine 4% with epinephrine 1:100000

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Healthy patients; aged 18 to 65 years; No allergy to lidocaine or articaine with 1:100,000 epinephrine; No pregnancy; having mandibular molars teeth with irreversible pulpitis and normal periapical radiographic appearance; Clinical diagnosis of irreversible pulpitis was confirmed by a positive response to an electric pulp test and a prolonged response with moderate to severe pain to a cold test using Roeko Endo-Frost . Exclusion criteria: presence of periodontal ligament (PDL) widening or periapical radiolucency; recently taken nervous system depressant or analgesic medication within 12 hours before treatment; absence of vital coronal pulp tissue during access preparation; failure to report lip numbness 10 minutes after Inferior alveolar nerve block injection.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Befor intervention and 10 minutes after intervention. Method of measurement: Heft- parker Visual analog scales.	—

Secondary

Measure	Time frame
Pulp sensivity. Timepoint: Before injection and 10 minutes after injection. Method of measurement: Electerical pulp test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Omid Dianat

Dental School of Shahid Beheshti University of Medical Science

omiddianat@gmail.com+98 21 2240 3075

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026