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Analgesic effect of nitroglycerin additive to lidocaine in intravenous regional anesthesia

Evaluation of analgesic effect of nitroglycerin additive to lidocaine in intravenous regional anesthesia in forearm surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015072712642N17
Enrollment
70
Registered
2015-08-15
Start date
2015-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The intravenous regional anesthesia. Anaesthetics and therapeutic gases

Interventions

Intervention 1: In the control group local anesthetic solution of 3miligeram per kilogeram body weight lidocaine with a concentration of 0.5percentage diluted with normal saline will injected via intr
Prevention
In the control group local anesthetic solution of 3miligeram per kilogeram body weight lidocaine with a concentration of 0.5percentage diluted with normal saline will injected via intravenous cannula
In the Intervention group local anesthetic of 3 miligeram per kilogeram body weight lidocaine with a concentration of 0.5percentage addition to 200 microgeram nitroglyserine injected via intravenous c

Sponsors

Vice Chancellor for research of Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: non urgent surgery; age more than 20 years. Exclusion criteria: Sickle cell anemia; Raynaud's phenomena; history of use of nitroglycerine; history of use of sildenafil in 24 hours ago; history of allergy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Patient's tourniquet pain. Timepoint: At 5, 10, 15, 20, 40 minutes after the start of operation will be evaluated. Method of measurement: According to VAS score.;Venous oxygen saturation. Timepoint: Before and after use tourniquet. Method of measurement: By pulse oximetry based on mmHg.

Secondary

MeasureTime frame
Blood Pressure. Timepoint: Before and after use tourniquet. Method of measurement: By mercury sphygmomanometer based on mmHg.;Heart Rate. Timepoint: Before and after use Tourniquet. Method of measurement: By pulse oximetry based on the number of minutes.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026