Alzheimer's disease. Alzheimer disease with late onset
Conditions
Interventions
Intervention 1: intervention group: curcumin capsule, twice a day for 12 weeks. Intervention 2: control group:placebo of curcumin, twice a day for 12 weeeks.
Treatment - Drugs
Placebo
intervention group: curcumin capsule, twice a day for 12 weeks
control group:placebo of curcumin, twice a day for 12 weeeks
Sponsors
Vice Chancellor for Baghiyatallah University of Medical Sciences, Chemical Injeries Research Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion Criteria : Sign informed consent ; mild Alzheimer; with out any of psychic disorder Exclusion Criteria : Discontinue of treatment more than 2 weeks ; disese becomes out of control ; allergic reaction to herbal compounds ,abnormal results in lab tests
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvment of mental state. Timepoint: before and after of intervention (12 weeks). Method of measurement: MMSE questionaire.;Improvment of quality of life. Timepoint: before and after of intervention (12 weeks). Method of measurement: quality of life questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Interleukin18 (IL18). Timepoint: befor and after of intervention(12 weeks). Method of measurement: level of serum.;Superoxide dismutase (SOD). Timepoint: before and after of intervention(12 weeks). Method of measurement: level of serum.;Glutathione peroxidase (GPO). Timepoint: before and after of intervention(12 weeks). Method of measurement: level of serum.;Malondialdehyde(MDA). Timepoint: befor and after of intervention(12 weeks). Method of measurement: level of serum. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahsa Bakhtiyari
Pharmaceutical Sciences Branch Islamic Azad University
Outcome results
None listed