Coronary Artery Bypass Graft Surgery. Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris
Conditions
Interventions
Intervention 1: Intervention group: Patients in the first group (20 patients) with standard interactions and treatments receive 1 g l-carnitine per liter of Cardioplegia solution. Intervention 2: Inte
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with mild-to-moderate heart failure (EF = 55-40%) for coronary artery bypass graft surgery (elective CABG)
Exclusion criteria
Exclusion criteria: History of seizure or epilepsy Patients with a history of cevebrovascular diseases Chronic liver failure (enzymes higher than 2 times normal) Chronic renal failure (STAGE 4 & 5) Drinking alcohol and drugs Coronary artery bypass surgery without using a bypass pump CABG surgery EF<40%
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum HS-CRP and IL-6 levels in three groups of patients. Timepoint: At baseline and 24 hours after surgery. Method of measurement: Blood sampling, blood serum isolation, and finally biochemical tests. | — |
Secondary
| Measure | Time frame |
|---|---|
| Measurement of serum levels of CPK-MB and Troponin in patients undergoing surgery. Timepoint: It will be measured at baseline 8 and 24 hours after surgery. Method of measurement: Blood sampling, blood serum isolation, and finally biochemical tests. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza jahangirifard
Shahid Beheshti University of Medical Sciences
Outcome results
None listed