The effect of positive end-expiratory pressure on O2 saturation

Impact of 5 and 10 cm positive end-expiratory pressure during anesthesia on post-operative O2 saturation in Post-Anesthetic Care Unit in patients undergoing general anesthesia for cesarean section compared with non-application of end-expiratory pressure

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015072423315N1

Enrollment

120

Registered

2016-02-27

Start date

2016-02-29

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anesthesia, respiratory disorder. post-operative respiratory disorder

Interventions

Intervention 1: Intervention 1 (Group A): No application of positive end-expiratory pressure (PEEP) during anesthesia

Measurement of oxygen saturation and vital signs before, during and after anesthesia. Intervention 2: Intervention 2 (Group B): Application of 5 cm H2O positive end-expiratory pressure (PEEP) during a

Prevention

Intervention 1 (Group A): No application of positive end-expiratory pressure (PEEP) during anesthesia

Measurement of oxygen saturation and vital signs before, during and after anesthesia

Intervention 2 (Group B): Application of 5 cm H2O positive end-expiratory pressure (PEEP) during anesthesia and measurement of oxygen saturation before, during and after anesthesia

Intervention 3 (Group C ): Application of 10 cm H2O positive end-expiratory pressure (PEEP) during anesthesia and measurement of oxygen saturation before, during and after anesthesia

Eligibility

Sex/Gender

Female

Age

15 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: elective cesarean section, Body Mass Index (BMI)<30, Age between 15 and 35 years Exclusion criteria: Cardiopulmonary disease, difficult intubation, pulmonary embolism, pneumothorax, post-operative shivering

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Arterial oxygen saturation. Timepoint: after arrival to operation room before the operation and every 15 minute during surgery and at the recovery arrival and every 15 minute thereafter until discharge. Method of measurement: Masimo pulse oxymeter in Saadat Monitoring.	—

Secondary

Measure	Time frame
Noninvasive arterial blood pressure. Timepoint: at the operating room arrival and every 15 minute during surgery and at the recovery arrival and every 15 minute thereafter until discharge. Method of measurement: Saadat Noninvasive Automatic Sphygmomanometer.;Heart rate. Timepoint: at the operating room arrival and every 15 minute during surgery and at the recovery arrival and every 15 minute thereafter until discharge. Method of measurement: Saadat Noninvasive Automatic Sphygmomanometer.	—

Measure

Time frame

Noninvasive arterial blood pressure. Timepoint: at the operating room arrival and every 15 minute during surgery and at the recovery arrival and every 15 minute thereafter until discharge. Method of measurement: Saadat Noninvasive Automatic Sphygmomanometer.;Heart rate. Timepoint: at the operating room arrival and every 15 minute during surgery and at the recovery arrival and every 15 minute thereafter until discharge. Method of measurement: Saadat Noninvasive Automatic Sphygmomanometer.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahmoud Ganjifard

Birjand University of Medical Sciences

ganjm@bums.ac.ir+98 56 3242 1449

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026