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Effect of General anesthesia on optimal extubation in mandibular fractures

Comparison of general anesthesia with isoflurane/N2O and propofol/alfentanil on optimal extubation in mandibular fractures with arch bar

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015072412642N16
Enrollment
60
Registered
2015-08-13
Start date
2014-11-30
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mandible fracture surgery. Fracture of mandible

Interventions

Intervention 1: In the first group after the induction maintenance of anesthesia will done in combination with a dose of 100 micrograms per kilogram body weight in minute propofol and one micrograms
Treatment - Drugs
Prevention
In the first group after the induction maintenance of anesthesia will done in combination with a dose of 100 micrograms per kilogram body weight in minute propofol and one micrograms per kilogram bod
In the first group after the induction maintenance of anesthesia will done in combination with 1%isoflurane and 50/50 mix oxygen and nitrous oxide

Sponsors

Vice Chancellor for research of Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Patient with ASA I; Age more than 15 years old. Exclusion Criteria: Patient with history of use of narcotic; Patient with history of use of anti hypertension drug; Patients with hypertension; Patient with age more than 50 years old.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Blood Pressure. Timepoint: From 5 minutes before induction to 15 minutes after induction with 5 minute intervals. Method of measurement: By mercury sphygmomanometer in mmHg.;Heart rate. Timepoint: From 5 minutes before induction to 15 minutes after induction with 5 minute intervals. Method of measurement: By pulse oximetry in terms of number of minutes.;Comfort during extubation. Timepoint: From 5 minutes before induction to 15 minutes after induction with 5 minute intervals. Method of measurement: According scored based on the elevation of the arm or leg and pressing hand of doctor.

Secondary

MeasureTime frame
Nausea. Timepoint: From 5 minutes before anesthesia to 24 hours after surgery. Method of measurement: According to the saying patient.;Vomitting. Timepoint: From 5 minutes before anesthesia to 24 hours after surgery. Method of measurement: According to the saying patient.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026