Lung injury in sulfur mustard victims. Chronic respiratory conditions due to chemicals, gases, fumes and vapours, Other respiratory conditions due to chemicals, gases, fumes and vapours
Conditions
Interventions
Drug: Placenta Placenta mesenchymal stem cell
Dosage: 100 million cells per patient
frequency: 4 times
Duration: 15 days interval
Injection method: vein injection.
Treatment - Other
Drug: Placenta Placenta mesenchymal stem cell
Dosage: 100 million cells per patient
frequency: 4 times
Duration: 15 days interval
Injection method: vein injection
Sponsors
Veterans Medical Science and Engineering Research Centre
Iranian Stem Cell Council
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients with a proven track record have mustard gas; Signed informed consent Exclusion criteria: Underlying disease
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: In enrolment stage and 6 months after the first cell injection. Method of measurement: St. George's questionnaire form. | — |
Secondary
| Measure | Time frame |
|---|---|
| Spirometry factors. Timepoint: Befor each cell injection and 3 and 6 months after the first cel injection. Method of measurement: spirometry.;Repair and inflammation factors of lung. Timepoint: In enrolment stage and 3 and 6 months after the first cell injection. Method of measurement: ELISA method.;HRCT findings. Timepoint: In enrolment stage and months after the first cell injection. Method of measurement: HRCT imaging. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarzad Parvizpour
Tehran University of Medical Sciences
Outcome results
None listed