Effect of local corticosteroid injection on prevertebral soft tissue swelling in cervical disc surgery

Comparing the effect of injection compared to no injection of local methylprednisolone on prevertebral soft tissue swelling during operation in patients with cervical discopathy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015072123270N1

Enrollment

Registered

2015-10-08

Start date

2015-08-17

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical disc. Cervical disc disorders

Interventions

Intervention 1: Intervention 1: Local injection of 80 milligram methylprednisolone acetate (injectable suspension) produced by caspiantamin factory into the retropharyngeal and prevertebral neck muscl

Treatment - Drugs

Intervention 1: Local injection of 80 milligram methylprednisolone acetate (injectable suspension) produced by caspiantamin factory into the retropharyngeal and prevertebral neck muscles by 5 millilit

Intervention 2: In this group at the end of operation no injection into the prevertebral and retropharyngeal muscles is used.

Eligibility

Sex/Gender

All

Age

20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with radiculopathy or myelopathy due to cervical disc involving one or two segments. Exclusion criteria: Cervical disc herniation more than two segments; history of previous surgery in same area; need to corpectomy; Herniated disc due to cervical trauma or infection or tumor; underlying diseases such as rheumatoid arthritis; diabetes and chronic heart or renal diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Prevertebral soft tissue swelling in third to seventh cervical vertebrae. Timepoint: One day before, two days after and ten days after operation. Method of measurement: Measurement by lateral cervical radiography.	—

Secondary

Measure	Time frame
Local pain in operation site. Timepoint: Two days and ten days after operation. Method of measurement: Visual analogue scale.;Dysphagia. Timepoint: Two days and ten days after operation. Method of measurement: Dysphagia scaling table.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen hasani barzi

Qazvin University of Medical Sciences

drbarzi2002@yahoo.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026