Oral mucositis. Oral mucositis (ulcerative)
Conditions
Interventions
Intervention 1: Intervention group: Barhang mouthwash solution 10%, 4 times a day, each time in the amount of 8 ml and two minutes for 10 days. Intervention 2: Control group: Combined mouthwash (conta
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age of 18 years or more Hospitalization, hematopoietic cell transplant department Suffering from grade 1, 2 or 3 mucositis according to the WHO scale following chemotherapy preparation for hematopoietic cell transplantation. Informed consent to participate in the study
Exclusion criteria
Exclusion criteria: Radiotherapy Use of other mouthwashes Use of artificial saliva products Taking antidepressants Taking systemic antihistamines Alcohol consumption Having an underlying rheumatological disease Having oral candidiasis Oral herpes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the average intensity of mucositis and pain intensity. Timepoint: Pain intensity on the fourth, seventh and end days of the intervention, as well as the number of patients with mild, moderate and severe mucositis. Method of measurement: The severity of mucositis is based on the WHO scale and the pain intensity evaluation criterion is the VAS (visual analog scale). | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of possible cases of complete recovery (reaching zero grade) during the intervention. Timepoint: End of ontervention (10th day). Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactsoltani@pharm.mui.ac.ir
Esfahan University of Medical Sciences
Outcome results
None listed