Effect of pentoxifylline topical ointment on wound healing

Evaluation of the effect of 10% pentoxifylline topical ointment on pressure ulcer healing

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150721023282N18

Enrollment

Registered

2021-07-25

Start date

2021-07-06

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bedsore.

Interventions

Intervention 1: Intervention group: Topical ointment 10% pentoxifylline (made by faculty of pharmacy of Isfahan university of medical sciences), once daily concurrent with routine wound care including

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Infection of stage 2 or 3 bedsores in one or more areas

Exclusion criteria

Exclusion criteria: Smoking now Use of immunosuppressive drugs in the last 3 months Having a coagulation disorder (such as hemophilia) Use of medications or supplements effective in wound healing (phenytoin, glucocorticoids, anticancer drugs and products containing vitamin C, vitamin A or Zinc) in the last 3 months

Design outcomes

Primary

Measure	Time frame
Percent of Decrease in Ulcer Size. Timepoint: Baseline, 7 and 14 Days after Initiation of Intervention. Method of measurement: Ruler.	—

Secondary

Measure	Time frame
The Number of Cases with Peri-Ulcer Erythema. Timepoint: Baseline, 7 and 14 Days after Initiation of Intervention. Method of measurement: Observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRasool Soltani

Esfahan University of Medical Sciences

soltani@pharm.mui.ac.ir+98 31 3792 7067

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026