Knee osteoarthritis. M17.1
Conditions
Interventions
Intervention 1: Intervention group: Oily lotion of frankincense extract containing 65% boswellic acid (manufactured by Fardis pharmaceutical company), 3 times daily for 4 weeks. Intervention 2: Contro
Sponsors
Fardis pharmaceutical company
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: age of 40 - 80 years Osteoarthritis of at least one knee for at least 3 months based on the diagnostic criteria of American College of Rheumatology (ACR) Pain score > 4 mm based on the Visual Analogue Scale (VAS) Grade 2 or 3 of Kellgren-Lawrence scale in knee radiography within the past 3 months
Exclusion criteria
Exclusion criteria: Use of intra-articular glucocorticoids within the past 3 months Use of intra-articular sodium hyaluronate within the past 6 months Use of systemic glucocorticoids (either oral or parenteral) within the past 14 days Having other osteoarticular disorders (e.g., rheumatoid arthritis and gout) Skin disorder in knee region Sensitivity to prescribed topical formulations Knee arthroscopy within the past 3 months Illiteracy Unable to answer the questions Pregnancy Lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC Index. Timepoint: Before the intervention and 4 weeks after the intervention. Method of measurement: Questionnaire.;Visual analogue scale (VAS). Timepoint: Before the intervention and 4 weeks after the intervention. Method of measurement: scoring on the scale.;Patient global assessment (PGA). Timepoint: Before the intervention and 4 weeks after the intervention. Method of measurement: scoring on the scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRasool Soltani
Esfahan University of Medical Sciences
Outcome results
None listed