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Comparison of the anesthetic efficacy of articaine 4% in two supplemental anesthetic injections

Comparison of the anesthetic efficacy of articaine 4% as supplemental intraligamentary injection with buccal infiltration in posterior mandibular teeth with irreversible pulpitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015072023253N1
Enrollment
100
Registered
2016-08-17
Start date
2016-04-08
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irreversible pulpitis. Pulpitis

Interventions

Intervention 1: After inferior alveolar nerve block injection with lidocaine and epinephrine 1/80000, the supplemental buccal infiltration injection with articaine 4% and epinephrine 1/100000 will be

Sponsors

Shahid Behsehti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients older than 18 without any systemic diseases First or second mandibular molars with irreversible pulpitis No periapical lesion in radiography Prolonged response with moderate to severe pain to cold test and check the vitality by electrical pulp tester Vital coronal pulp tissue

Exclusion criteria

Exclusion criteria: Allergy to lidocaine or articaine Lactate or pregnancy Using analgesic drugs since 12 hours before the treatment Mobility more than 0.5mm Probing more than 3mm Severe dental pain needs emergency treatment Teeth with full crowns No lip numbness after the Inferior Alveolar Nerve Block injection No pulp exposure after removing caries

Design outcomes

Primary

MeasureTime frame
Anesthesia. Timepoint: After inferior alveolar nerve block injection, after supplemental injection. Method of measurement: Electrical pulp tester.;Pulse. Timepoint: Before inferior alveolar nerve block injection, after inferior alveolar nerve block injection, after supplemental injection. Method of measurement: Pulse-oximetre.;Pain during injection. Timepoint: Pain during inferior alveolar nerve block and supplemental injection. Method of measurement: Heft Parker Visual Analogue Scale.;Pain. Timepoint: After inferior alveolar nerve block and supplemental injection. Method of measurement: Heft Parker Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazanin Zargar

Shahid Beheshti University of Medical Sciences

nzargar48@yahoo.com+98 21 2217 5350

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026