Allergic Rhinitis. Perennial allergic rhinitis
Conditions
Interventions
Subcutaneous injection of condensed allergens based on the approved protocol of American Academy of Asthma, Allergy and Immunology.
Treatment - Other
Subcutaneous injection of condensed allergens based on the approved protocol of American Academy of Asthma, Allergy and Immunology
Sponsors
Mashhad University of Medical Sciences, Vice chancellor for research
Eligibility
Sex/Gender
All
Age
10 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: All patients with persistent allergic rhinitis aged 45-10 years; Residence in Mashhad that have positive skin test to the local common aeroallergens and are willing to cooperate in the project. Exclusion criteria: Patients with seasonal allergic rhinitis, patients who have a history of autoimmune disease;Patients who consumed steroids or immunosuppressive drugs and effective on immune system; Pregnant women; Patients with immune deficiencies diseases, Patients with allergic asthma; Patients with malnutrition
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cytokines Variations. Timepoint: Comparison baseline and terminal sample, after one year of treatment course. Method of measurement: Measuring selective cytokines by Real time PCR. | — |
Secondary
| Measure | Time frame |
|---|---|
| Systemic reactions to immunotherapy. Timepoint: Each immunotherapy session. Method of measurement: Clinical evaluation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mohammad Ali Zamani
Mashhad University of Medical Sciences
Outcome results
None listed